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Endogenous cannabinoids (endocannabinoids) are synthesised on demand from acids in cell membranes
The enzyme 2-AG degrades excess cannabinoids
THC binds in high concentrations in the cortex
The ECS can affect pain/trauma/seizure signals through a process of retrograde signalling.
CB1 and CB2 are ionotropic receptors
THC primarily binds CB1 and is the mirror image of anandamide
Which conversion is an example of decarboxylation?
Flavonoids are the most common plant chemical in nature
Pinene is a bronchodilator
Terpenes may act in synergy with cannabinoids and increase the therapeutic effect
One of the disadvantages of dried cannabis flower is that it degrades easily
A vape pen increases exposure to products of combustion
Metabolism of THC in the liver produces a less potent product
Topical cannabis creams and lotions are non-intoxicating
There are concerns about residual solvent in the end product after hydrocarbon extraction
The starting dosage for THC in edibles is:
Phytocannabinoids can decrease IL-8 production in tumour cells
CB1 and CB2 receptor expression is up-regulated in human prostate cancer
Pain is usually treated with CBD dominant strains
A 99.5% CBD isolate was approved by the FDA to treat: